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Bleeding peptic ulcer: Acid enhances clotdissolution promoting ulcer bleed. The smaller cell represents a laterstage ofa polychromatophilic erythroblast

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Earlier work showed an interaction of the R248W and R273H mutantforms of p53 with Mre11, which is a part of the MRN complex (Mre11/Rad50/NBS1) that is involved in the initial sensing of DNA DSBs and subsequent recruit-ment of ATM [94]. Petitjean A, Achatz MIW, Borresen-Dale AL et al (2007) TP53 mutations in human cancers:functional selection and impact on cancer prognosis and outcomes

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Studies on bioabsorbable bone substitutes (BBS)impregnated with antibiotics for the management of IAOM have been recentlyreported [62–64].

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